Residual Gastric Content and GLP-1

Recruiting now

Conditions studied: Pre-op Gastric Emptying

In brief

Studies have shown that even following the fasting guideline, patients on GLP-1 still have residual gastric content which increases their risk of aspiration during anesthesia. We aim to investigate the prevalence of full stomachs following different fasting times.

Key facts

Study ID

NCT06814080

Run by

University of Arkansas

People needed

45

Starts

2025-05-22

Expected to finish

2026-08-01

Last updated by the study team

2025-09-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age ≥ 18 yr. ASA physical status I- III Elective surgery

You may not qualify if…

• Pregnancy
• History of upper gastrointestinal disease or previous surgery on the esophagus, stomach or upper abdomen;
• Documented abnormalities of the upper gastrointestinal tract such as gastric tumors; recent upper gastrointestinal bleeding (within the preceding 1 month).
• Medicines that may delay gastric emptying (e.g., anticholinergic agents, opioid)
• ASA class IV or above
• Unable to understand English
• Cardiac cases with low ejection fraction
• Elderly patients above 65 years of age
• Liver or renal transplant cases
• Type 1 diabetes Patients on insulin or sulphonylurea medication

Where it is running

• University of Arkansas for Medical Science — Little Rock, Arkansas, United States (enrolling)

Full record on ClinicalTrials.gov

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