Prospective Analysis of Circulating Nucleosomes in Patients Receiving a First Line Treatment for a Non-Hodgkin Lymphoma

Recruiting now · Not applicable

Conditions studied: Follicular Lymphoma, Diffuse Large B-Cell Lymphoma

In brief

The goal of this study is to prospectively follow the level of circulating nucleosomes in patients treated for a non-Hodgkin lymphoma and determine whether it correlates with the clinical response.

Key facts

Study ID

NCT06813573

Run by

Gustave Roussy, Cancer Campus, Grand Paris

People needed

50

Starts

2024-09-30

Expected to finish

2029-10-01

Last updated by the study team

2025-02-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Histologically proven diagnosis of diffuse large B cell lymphoma or follicular lymphoma, according to the WHO 2016 classification, requiring a first line of treatment with a RCHOP 21 regimen
• Agreement to participate after receiving oral and written information on the study

You may not qualify if…

• History of previous treatment for lymphoma (excluding localized low dose radiotherapy in the case of follicular lymphoma)
• Treatment with a chemotherapy regimen different from RCHOP21

Where it is running

• Gustave Roussy — Villejuif, France (enrolling)

Full record on ClinicalTrials.gov

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