Polyphenol Metabotypes in People With Diabetes Type 2
Recruiting now
Conditions studied: Type 2 Diabetes Mellitus (T2DM)
In brief
This cross-sectional study seeks to characterize the overall polyphenol metabotype in patients with T2DM in comparison to age-matched individuals without diabetes. Additionally, the study aims to identify factors that influence the polyphenol metabotype (transit time and gut microbial capacity to degrade polyphenols in particular).
Key facts
- Study ID
- NCT06810635
- Run by
- University Hospital, Ghent
- People needed
- 100
- Starts
- 2026-03-04
- Expected to finish
- 2028-12-01
- Last updated by the study team
- 2026-03-23
Who can join
Age: 40 and older, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- all participants
- between 40-85 years
- age-matched individuals without diabetes
- BMI between 18.5-30
- no metabolic syndrome
- persons with T2DM
- at leats 2 years of clinical diagnoses of T2DM
- stable medication use for at least 1 month
You may not qualify if…
- pregnancy of breastfeeding
- in last month
- acute use of anti/pre/probiotics
- start of new drug or dietary supplements
- major changes in diet
- major lifestyle changes
- diseases
- Gastrointestinal diseases (inflammatory bowel disease)
- Bariatric surgery
- Other forms of diabetes (cystic fibrosis/MODY/T1DM)
- Heart problems (NYHA 3/4) or previous cardiovascular events
- Liver problems: non-alcohol steatohepatitis (NASH) and cirrhosis
- Lung problems (COPD - GOLD 3/4), cystic fibrosis
- Uncontrolled thyroid function disruption in the past 6 months
- Intake of coumarin derivatives and direct oral anticoagulant medication
- Anti-cancer treatment: chemo-/immunotherapy
- Immonosuppressants (transplant)
- Antiepileptic drugs
Where it is running
- Department of rehabilitation sciences - UGent — Ghent, Belgium (enrolling)
- Ghent University — Ghent, East Flanders, Belgium
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.