Monitoring & Mitigation of Neurologic Injuries to Optimize Resilience After Repetitive Head Impacts
Enrolling by invitation · Not applicable
Conditions studied: Head Injuries
In brief
The purpose of this Phase 2, double-arm study is to identify repetitive, non-concussive head impacts that impair neurologic functioning, and to test treatments that can mitigate these effects and return functioning to normal as quickly as possible.
Key facts
- Study ID
- NCT06810193
- Run by
- University of Rochester
- People needed
- 350
- Starts
- 2025-07-23
- Expected to finish
- 2029-12-01
- Last updated by the study team
- 2025-09-11
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age ≥ 18 years
- Collegiate athlete or athlete-cadet anticipated to be an active member of a varsity sport team.
You may not qualify if…
- Any head, neck, or face injury in the 3 months prior to enrollment that precludes participation in contact sports or wearing a mouth guard sensor
- History of neurological or psychiatric disorders or neurological disorders that impact electrical activity in the brain (such as seizure disorders), or diagnosed learning disability, that in the opinion of the investigator, would interfere with participation in the study.
- Participants currently undergoing active treatment for migraine, depression and/or anxiety or ADHD will not be excluded as these are high prevalence conditions in the adolescent and collegiate population (8-30%). However, exploratory stratified analyses will be conducted where possible.
- Participants with eye conditions or diseases that could impact the blood vessels in the eye.
- Determination that the participant is unsuitable for study entry or potentially unable to complete all aspects of the study based on the judgement of the Site Investigator or Study PI.
Where it is running
- University at Buffalo — Amherst, New York, United States
- University of Rochester — Rochester, New York, United States
- The Citadel, The Military College of South Carolina — Charleston, South Carolina, United States
Full record on ClinicalTrials.gov
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