A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Running, not enrolling · Phase 3 · Has a placebo group

Conditions studied: Generalized Anxiety Disorder

In brief

A Phase 3, Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating DT120 Compared to Placebo in Generalized Anxiety Disorder - Panorama

Key facts

Study ID

NCT06809595

Run by

Definium Therapeutics US, Inc.

People needed

245

Starts

2025-01-29

Expected to finish

2027-05-01

Last updated by the study team

2026-06-22

Who can join

Age: 18 and older, up to 74. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of GAD per DSM-5
• Male or female aged 18 to 74
• HAM-A Total Score ≥20

You may not qualify if…

• Certain psychiatric disorders (other than generalized anxiety disorder)
• First degree relative with or lifetime history of a psychotic disorder or bipolar disorder
• Current diagnosis of alcohol or substance use disorder (excluding nicotine and caffeine)
• Any clinically significant unstable illness

Where it is running

• Preferred Research Partners, Inc. — Little Rock, Arkansas, United States
• Psychedelic Science Institute — Los Angeles, California, United States
• West Los Angeles VA Medical Center — Los Angeles, California, United States
• Bradenton Research Center, Inc. — Bradenton, Florida, United States
• Clinical Neuroscience Solutions, Inc — Orlando, Florida, United States
• Atlanta Center for Medical Research — Atlanta, Georgia, United States
• Sheppard Pratt Health System — Towson, Maryland, United States
• Adams Clinical Boston — Boston, Massachusetts, United States
• Princeton Medical Institute — Princeton, New Jersey, United States
• University of Cincinnati Psychiatry- Anxiety Disorders Research Program — Cincinnati, Ohio, United States
• Neuro-Behavioral Clinical Research, Inc. — North Canton, Ohio, United States
• Austin Clinical Trial Partners — Austin, Texas, United States
• Cedar Clinical Research — Murray, Utah, United States
• Core Clinical Research — Everett, Washington, United States
• A-shine s.r.o. — Pilsen, Czechia
• Institut Neuropsychiatricke Pece (INEP) — Prague, Czechia
• Psyon s.r.o. — Prague, Czechia
• Cabinet Dr.Desbonnet : Résidence Saint Michel — Douai, France
• Hôpital Conception, CIC Centre, bat néphrologie 3eme étage — Marseille, France
• CMME — Paris, France
• GHU Paris Psychiatrie et Neurosciences — Paris, France
• Centre Hospitalier du Rouvray — Sotteville-lès-Rouen, France
• Department of Psychiatry and Psychotherapy Campus Charité Mitte Charité Universitätsmedizin Berlin — Berlin, Germany
• OVID Clinic Berlin — Berlin, Germany
• Central Institute of Mental Health — Mannheim, Germany

Full record on ClinicalTrials.gov

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