Exercise and Endocannabinoids for Brain and Mental Health

Completed · Not applicable

Conditions studied: Children, Adolescents

In brief

This study will explore how exercise affects brain chemicals called endocannabinoids, which may improve thinking skills and reduce feelings of stress, anxiety, and low mood in children and teens aged 9 to 17. Participants will take part in a single 30-minute activity session, where they will be randomly assigned to one of three groups: 1. Moderate-intensity exercise (walking or running on a treadmill at 50-70% of their maximum heart rate). 2. Light stretching (gentle movements at less than 40% of their maximum heart rate). 3. Seated meditation (relaxing without movement at less than 30% of their maximum heart rate). The investigators will measure endocannabinoid levels, thinking skills, and mood before and after the activity to see how these activities affect the brain and emotions.

Key facts

Study ID

NCT06808490

Run by

Wayne State University

People needed

68

Starts

2021-12-21

Expected to finish

2024-03-18

Last updated by the study team

2025-02-05

Who can join

Age: 9 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Provision of signed and dated informed consent form
• Stated willingness to comply with all study procedures and available for the duration of the study
• 9-17 years of age
• Adolescent and parent/guardian are English-speaking, as study assessments are in English
• Right-handed

You may not qualify if…

• Head injury
• Sensory (e.g., hearing) impairment
• Physical (e.g., motor, balance) impairment
• Physical disabilities
• Neurological disorders
• Any condition that would contraindicate blood draws

Where it is running

• Tolan Park Medical Building — Detroit, Michigan, United States

Full record on ClinicalTrials.gov

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