The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery

Running, not enrolling · Phase 4

Conditions studied: Hand Surgery, Wrist Surgery, Elbow Surgery, Fracture Fixation, Dupuytren Contracture, Finger Fracture, Wrist Arthropathy, Distal Radius Fracture

In brief

Patients undergoing hand, wrist, and elbow surgery may experience pain after surgery. The orthopedic surgeon may provide prescription pain medications after surgery to assist with pain control. However, with concern of the opioid epidemic, many patients would rather minimize the use of narcotic pain prescriptions after having surgery. As an alternative, ultrasound guided regional nerve blocks can assist with postoperative pain control. patients consented to this study will be randomized into three groups: 1) will receive an ultrasound guided nerve block with local anesthesia only, 2) will receive an ultrasound guided nerve block with local anesthesia and a steroid dexamethasone, 3) will receive an ultrasound guided nerve block with liposomal bupivacaine. our study team will make phone calls after surgery to the patient to determine how long the block lasted for, and how many opioid pain pills were taken up to 3 days after surgery.

Key facts

Study ID

NCT06806410

Run by

St. Luke's Hospital, Pennsylvania

People needed

120

Starts

2023-05-01

Expected to finish

2025-01-30

Last updated by the study team

2025-02-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• patients scheduled to undergo finger, hand, wrist, elbow surgery with a hand surgeon at St. Luke's University Hospital in Bethlehem, Pennsylvania
• patients greater than 18 years of age, able to provide written consent for surgery and study

You may not qualify if…

• patients that cannot provide written consent for finger, hand, wrist, elbow surgery
• patients with known allergies to local anesthetics
• patients with severe liver disease
• patients with a condition known as methemoglobinemia

Where it is running

• St. Luke's University Health Network — Bethlehem, Pennsylvania, United States

Full record on ClinicalTrials.gov

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