VExUS in Ards Patients and Association with AKI

Recruiting now

Conditions studied: Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

In brief

A single-center prospective observational study will be conducted with the aim of determining the prevalence of venous congestion during ARDS using venous Doppler and the VExUS score.

Key facts

Study ID

NCT06805409

Run by

Assistance Publique - Hôpitaux de Paris

People needed

120

Starts

2024-12-02

Expected to finish

2027-12-09

Last updated by the study team

2025-02-03

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients ≥18 years old
• Moderate to severe ARDS according to the Berlin definition
• Requiring catecholamine support
• Undergoing invasive mechanical ventilation for less than 48 hours

You may not qualify if…

• Patients presenting with acute kidney injury KDIGO III requiring renal replacement therapy before the initial ultrasound evaluation
• Requirement for veno-venous or veno-arterial ECMO circulatory support before inclusion
• Patients with end-stage chronic kidney disease, on dialysis, and/or kidney transplant recipients
• History of Child C cirrhosis and/or liver transplantation and/or portal hypertension
• History of portal thrombosis
• Known history of pulmonary hypertension
• Pregnant women
• Patients under legal protection
• Patients who have expressed opposition to participating in the research

Where it is running

• Armand MEKONTSO DESSAP — Créteil, Val de Marne, France (enrolling)

Full record on ClinicalTrials.gov

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