Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study
Recruiting now · Not applicable
Conditions studied: Vaping
In brief
The purpose of this study is to assess the effects of non-invasive vagus nerve stimulation (nNVS) on cognitive functioning in the users of e-cigarettes or vaping products. The investigators will use a digital wellness companion product (TRUVAGA™ device) that provides mild transcutaneous nVNS. The participants will be randomized to receive either a 2-min nNVS stimulation or control stimulation in the neck region followed by completion of three cognitive tests of attention and executive function.
Key facts
- Study ID
- NCT06804109
- Run by
- Temple University
- People needed
- 100
- Starts
- 2025-03-18
- Expected to finish
- 2028-02-09
- Last updated by the study team
- 2026-03-06
Who can join
Age: 18 and older, up to 25. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy young adults
- Age range 18-25 years
- Current or prior users of e-cigarettes
You may not qualify if…
- Participants will be excluded from the study if they:
- Have any rash, infection, swelling, cut, soreness, drug patch, surgical scar on the neck area
- Have any implantable medical device in their body such as a pacemaker, hearing aid implant, or any other metallic/electronic device
- Have any hearing or vision problems that are not corrected
- Are pregnant or breastfeeding
- Have any learning disabilities
- Have a medical history of any of the following condition
- Meningitis
- Traumatic brain injury
- Seizure
- Syncope
- Schizophrenia
- Schizoaffective disorder
- Bulimia (eating disorder)
- Other serious neurological illness
- Have a medical history of any of the following cardiac disorder
- Carotid atherosclerosis or carotid artery disease
- Cervical vagotomy
- First degree atrioventricular block or prolonged QT interval
- Are taking any medications for to treat hypertension, arrhythmias, or are on calcium channel blockers
Where it is running
- Temple University — Philadelphia, Pennsylvania, United States (enrolling)
Full record on ClinicalTrials.gov
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