Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments

Recruiting now · Not applicable

Conditions studied: Mild-moderate Cognitive Impairment

In brief

The goal of this clinical trial is to test a twice a week, moderate intensity exercise and coaching program (an in-person group and a distance group) for adults with mild-moderate cognitive impairments living in South Carolina. The main questions it aims to answer are: 1. Is the program practical to conduct, and it is acceptable and enjoyable? The hypothesis is that it will be possible to recruit participants, obtain the desired dosage of moderate intensity fitness and strength training twice a week for both groups. 2. Are their changes at 3, 6, 9 and 12 months in endurance, mobility, cognitive function and perception of cognitive function? The hypotheses are that endurance, strength and mobility will improve and cognitive measures will not decline (remain the same or improve) for both groups.

Key facts

Study ID

NCT06799429

Run by

University of South Carolina

People needed

50

Starts

2026-03-13

Expected to finish

2026-11-17

Last updated by the study team

2026-06-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• adult (age >18)
• medical diagnosis of mild-moderate cognitive impairment
• medical clearance by referring provider for exercise
• able to follow 2-step commands

You may not qualify if…

• significant pain with movement (>5/10)
• severe balance impairments or lack of independence on and off exercise equipment (by physical therapist judgment at Intake)

Where it is running

• Arnold School of Public Health — Columbia, South Carolina, United States (enrolling)
• Sumter YMCA — Sumter, South Carolina, United States (enrolling)

Full record on ClinicalTrials.gov

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