Auricular VNS Following Intracerebral Hemorrhage

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Intracerebral Hemorrhage

In brief

This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following intracerebral hemorrhage.

Key facts

Study ID

NCT06799390

Run by

Washington University School of Medicine

People needed

80

Starts

2025-04-06

Expected to finish

2032-02-09

Last updated by the study team

2026-07-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients who present with a spontaneous supratentorial intracerebral hemorrhage (ICH) to Barnes Jewish Hospital

You may not qualify if…

• Patients < 18 years old
• Patients with a presumed traumatic etiology for their ICH, infratentorial location, ICH volume > 60 ml or < 10 ml, at risk of imminent death (e.g. Glasgow Coma Scale, GCS of 3 or one or more pupils unreactive), surgical intervention imminently planned (not including ventriculostomy)
• Patients undergoing active cancer therapy
• Patients with sustained bradycardia on arrival with a heart rate < 50 beats per minute.
• Patients who cannot be enrolled within 48 hours of the initial bleed.

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States (enrolling)

Full record on ClinicalTrials.gov

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