How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?

Starting soon · Not applicable · Has a placebo group

Conditions studied: Iron Deficiency Anemia Treatment, Iron Deficiency, Iron Deficiency (Without Anemia)

In brief

The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and quality of life. The main questions it aims to answer are: * What is the association between iron status, cognitive function, mood, quality of family relationships, and quality of life in perimenopausal women? * How does iron repletion, via supplementation, affect cognitive function, mood, quality of family relationships, and quality of life in perimenopausal women? The investigators will compare the effect of iron supplements to a placebo (gelatin capsule) to see if iron supplements could improve iron status, cognitive function, mood, quality of family relationships, and quality of life of iron-deficient and/or anemic women undergoing the menopausal transition. Each participant will: * Make 2 visits (about 2 hours each - baseline and endline) to the Clinical Research Center at Purdue * Make a very brief visit at midpoint (about 10 minutes) for a checkup * Take a daily study supplement or placebo for 4 months

Key facts

Study ID

NCT06798584

Run by

Purdue University

People needed

240

Starts

2025-03-01

Expected to finish

2025-12-01

Last updated by the study team

2025-02-13

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Undergoing natural perimenopause
• English-speaking
• In general good health as documented by each woman's personal report that the participant is without any past history of a chronic health condition

You may not qualify if…

• Taking psychoactive drugs
• A history of hematological disorders

Where it is running

• Stone Hall — West Lafayette, Indiana, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.