Optical Coherence Tomography Angiography in Neurological Disease

Completed

Conditions studied: Octa, Stroke, Subarachnoid Hemorrhage, Intracerebral Hemorrhage

In brief

Optical Coherence Tomography Angiography (OCTA) is a non-invasive tool that images the neurovascular structures of the eye by using near-infrared light. Previous literature has demonstrated the potential of OCTA as a screening tool in stroke, but its utility in other neurological illness such as intracranial hemorrhage is unclear. Hence, this pilot study will gather preliminary data to support future grant applications to investigate this area more fully by recruiting patients with neurological illness and healthy controls and comparing their OCTA imaging parameters.

Key facts

Study ID

NCT06797765

Run by

University of Texas Southwestern Medical Center

People needed

7

Starts

2024-10-20

Expected to finish

2026-05-20

Last updated by the study team

2026-05-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18 years or older
• Patient admitted to the neuroscience intensive care unit with a diagnosis of: subarachnoid hemorrhage, intracerebral hemorrhage, intracranial aneurysm (ruptured or unruptured), intracranial vascular malformation, ischemic stroke, seizure disorder, intracranial infection, intracranial tumor(s), inflammatory demyelinating disease, traumatic brain injury and/or neuromuscular respiratory failure OR subjects from the community without major neurologic, cardiovascular, pulmonary or metabolic disease

You may not qualify if…

• Pregnancy
• Non-English speaking
• GCS motor score less than 6 (i.e. must be able to follow commands)
• Temporary or permanent physical limitation that renders the patient unable to sit up and look inside OCTA device

Where it is running

• UT Southwestern Medical Center — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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