Symptoms, Respiratory Dysfunction and Frailty Level in Allergic and Eosonophilic Asthmatics

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Conditions studied: Asthma, Respiratory Disease, Fragility

In brief

The aim of this study is to determine the level of respiratory dysfunction, symptoms and frailty in patients with asthma according to different endophenotypes (allergic and eosonophilic asthma). In the light of the data obtained, it is thought that rehabilitation approaches that can be determined according to different endophenotypes in line with the evaluated parameters will guide health professionals working in this field. Hypotheses H0: There is no difference between allergic and eosonophilic asthmatics in terms of pulmonary function, respiratory dysfunction, symptoms, dyspnoea, fatigue, rhinitis, perception of breathlessness in activities of daily living, asthma control, level of frailty or quality of life. H1: There is a difference between individuals with allergic and eosonophilic asthma in terms of pulmonary function, respiratory dysfunction, symptoms, dyspnoea, fatigue, rhinitis, perception of breathlessness in activities of daily living, asthma control, level of frailty or quality of life.

Key facts

Study ID

NCT06796894

Run by

Hacettepe University

People needed

60

Starts

2024-08-01

Expected to finish

2026-12-01

Last updated by the study team

2025-12-29

Who can join

Age: 35 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 35-75 years,
• Diagnosed with allergic or eosonophilic asthma according to the Global Strategy for the Prevention and Treatment of Asthma (GINA).

You may not qualify if…

• Known cognitive impairment,
• Having had an acute asthma attack in the last 6 weeks,
• Having changed medication in the last 4 weeks.

Where it is running

• Hacettepe University — Ankara, State, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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