Prospective Exploratory Study on rTMS for Migraine Under the Guidance of MEG
Recruiting now · Not applicable
Conditions studied: Migraine Disorders, Brain, rTMS Stimulation
In brief
Using magnetoencephalography to locate and regulate targets in migraine patients, repeating transcranial magnetic stimulation to physically regulate targets, and evaluating the safety and effectiveness of this treatment method through headache related scales. Using whole genome data and scale scores for correlation analysis, and conducting randomized controls with traditional drugs to explore new approaches for migraine.
Key facts
- Study ID
- NCT06796725
- Run by
- Ruijin Hospital
- People needed
- 60
- Starts
- 2025-02-06
- Expected to finish
- 2026-06-30
- Last updated by the study team
- 2025-02-11
Who can join
Age: 15 and older, up to 50. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Complies with specific disease diagnosis: A. Headaches that meet the criteria of B and C (headaches that meet the characteristics of tension headaches or migraines) should occur at least 15 days per month and last for at least 3 months; B. Headaches that meet the criteria of 1.1 migraine without aura diagnosis B-D or 1.2 migraine with aura B and C occurring at least 5 times; C. Headache meets any of the following criteria and occurs for more than 8 days per month, lasting for more than 3 months: ①1.1 C and D of migraine without aura②1.2 B and C of migraine with aura③ The migraine attack perceived by the patient can be relieved by taking triptan or ergot, which cannot be better explained by other diagnoses in ICHD-3.
- Must be able to swallow tablets
- Signed and dated informed consent form Promise to comply with research procedures and cooperate in implementing the entire research process
You may not qualify if…
- Age under 15 years old; Accompanied by optic disc edema, focal symptoms and signs of the nervous system (except for typical visual and sensory precursors) or cognitive impairment; Sudden and rapidly peaking severe headaches (thunderous headaches)
- Accompanied by fever; New onset headaches in adults, especially after the age of 50; Headaches in patients with high coagulation risk
- New headache in patients with tumor or AIDS history; Headaches related to changes in body position;
- History of epileptic seizures
Where it is running
- Ruijin Hospital — Shanghai, China (enrolling)
Full record on ClinicalTrials.gov
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