MEASUREMENT OF CIRCULATING MUTATION BURDEN

Recruiting now

Conditions studied: Breast Carcinoma, Genetic Predisposition to Cancer, BRCA Mutation, cfMB, Mutation Burden

In brief

Cancer-free women with a hereditary predisposition to breast and/or ovarian cancer

Key facts

Study ID

NCT06792721

Run by

Centre Francois Baclesse

People needed

30

Starts

2025-07-04

Expected to finish

2027-12-30

Last updated by the study team

2025-07-08

Who can join

Age: 30 and older, up to 50. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Female participant
• Participant undergoing oncogenetic follow-up at the Centre François Baclesse
• Participant belonging to a pair of related biological siblings
• Within the sibling pair, one participant is a carrier of a hereditary predisposition linked to a BRCA1/2 mutation (case), and the other participant is not a carrier (control).
• Participant between 30 and 50 years of age
• Participant affiliated to a social security scheme
• Participant having given her consent to participate by signing an informed consent form prior to any specific study-related procedure.

Where it is running

• Centre François Baclesse — Caen, France, France (enrolling)

Full record on ClinicalTrials.gov

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