Effects of Ventilator Hyperinflation Versus Vibrocompression in Mechanically Ventilated Patients

Recruiting now · Not applicable

Conditions studied: Mechanically Ventilated Patients, Lung Compliance, Airway Clearance Impairment

In brief

The aim of the current study is to compare the effects of ventilator hyperinflation and vibrocompression on lung compliance in mechanically ventilated patients.

Key facts

Study ID

NCT06791798

Run by

Cairo University

People needed

81

Starts

2025-02-01

Expected to finish

2025-05-01

Last updated by the study team

2025-02-07

Who can join

Age: 35 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Eighty-one mechanically ventilated patients more than 48 hours up to 7 days
• Their ages range from 35 to 55 years old.
• Medical stability (mean arterial pressure > 60 < 110, systolic blood pressure > 80, diastolic blood pressure > 60, fraction of inspired oxygen < 60, positive end expiratory pressure (PEEP) <10)

You may not qualify if…

• Patients will be excluded if they have the following conditions or diseases:
• Unstable hemodynamics
• Fraction of inspired oxygen (FiO2) ≥ 0.6
• PEEP ≥ 10 cmH2O
• undrained pneumothorax and hemothorax or subcutaneous emphysema
• Pulmonary pathology (e.g., acute respiratory distress syndrome, exacerbation of chronic obstructive pulmonary disease, and acute pulmonary edema)
• Unstable neurological problems (raised intracranial pressure).
• Lung Cancer
• Recent/unhealed rib fracture
• Any disease obstructs our study.

Where it is running

• Kasr AL Ainy — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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