Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms

Recruiting now · Early Phase 1

Conditions studied: Menopause

In brief

The investigators aim to assess the interactions between the sympathetic nervous system and the vasculature in women across the menopause transition to better understand why aging women have a higher risk of cardiovascular disease.

Key facts

Study ID

NCT06787066

Run by

University of Missouri-Columbia

People needed

75

Starts

2025-07-10

Expected to finish

2026-12-01

Last updated by the study team

2025-09-15

Who can join

Age: 18 and older, up to 70. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Assigned female at birth
• 18-70 years of age
• Body mass index (BMI) <30 kg/m2

You may not qualify if…

• Assigned male at birth
• Pregnancy, breastfeeding
• Body mass index ≥30 kg/m2
• Oral hormonal contraception in last 6 months, history of hormone replacement therapy, oophorectomy
• Current smoking/nicotine use
• Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy
• Nerve/neurologic disease
• Cardiovascular, hepatic, renal, respiratory disease
• Blood pressure ≥140/90 mmHg
• Diabetes, Polycystic ovarian syndrome
• Communication barriers
• Prescription medications

Where it is running

• University of Missouri — Columbia, Missouri, United States (enrolling)

Full record on ClinicalTrials.gov

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