Investigating the Periodontal Status of Traditional and Heated Tobacco Product Users
Recruiting now
Conditions studied: Gingivitis and Periodontal Diseases
In brief
This cross-sectional observational study aims to compare the clinical and radiographic periodontal status, as well as gingival crevicular fluid volume, among cigarette smokers, heated-tobacco product users, and non-smokers. Specifically, the aim is to determine whether tobacco product users exhibit worse clinical parameters-such as probing pocket depth, bleeding on probing, plaque index, clinical attachment loss-along with greater radiographic bone loss and higher gingival crevicular fluid volume than non-smokers.
Key facts
- Study ID
- NCT06784817
- Run by
- Semmelweis University
- People needed
- 90
- Starts
- 2023-09-01
- Expected to finish
- 2025-03-01
- Last updated by the study team
- 2025-01-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Smokers who smoke at least one cigarette daily for the past 12 months.
- Exclusive users of heated tobacco products (e.g., IQOS), using them at least once daily for the past 12 months and not regular traditional cigarette smokers.
- Non-smokers who have never consumed tobacco in any form.
You may not qualify if…
- Users of electronic cigarettes, smokeless tobacco, waterpipes, or any other tobacco products.
- Dual users of tobacco products.
- Individuals diagnosed with systemic diseases.
- Edentulousness or severe tooth loss (fewer than 20 remaining teeth).
- Individuals who have taken antibiotics, steroids, or non-steroidal anti-inflammatory drugs in the past 90 days.
- Pregnant or breastfeeding women.
- History of periodontitis.
- Individuals refusing to sign the written informed consent form.
- Third molars are excluded from examination.
Where it is running
- Semmelweis University Department of Prosthodontics — Budapest, Pest County, Hungary (enrolling)
Full record on ClinicalTrials.gov
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