Fluoroscopic-Guided Bipolar Versus Monopolar Pulsed Radiofrequency for Refractory Trigeminal Neuralgia
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Trigeminal Neuralgia, Refractory Pain
In brief
A prospective exploratory study aiming at comparing pulsed bipolar versus pulsed unipolar radiofrequency ablation in patients with medically refractory trigeminal neuralgia.
Key facts
- Study ID
- NCT06779578
- Run by
- Alexandria University
- People needed
- 20
- Starts
- 2024-01-01
- Expected to finish
- 2025-09-01
- Last updated by the study team
- 2025-01-17
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with a definitive diagnosis of classical TN based on the third version of the International Classification of Headache Disorders (ICHD-3).
- Either purely paroxysmal classical TN or classical TN with concomitant chronic pain.
- Patients with idiopathic TN, with symptomatic clinical topography of V2 and/or V3.
- Patients with brain magnetic resonance imaging (MRI) unremarkable for structural etiology for the trigeminal pain.
- Patients with medically refractory TN defined as pain persisting beyond three months at a level of ≥5/10 after monotherapy or polytherapy in appropriate medical doses.
You may not qualify if…
- Painful trigeminal neuropathy based on the third version of the International Classification of Headache Disorders (ICHD-3).
- Trigeminal neuralgia with V1 symptomatic clinical topography.
- Trigeminal neuralgia comorbid with other atypical facial pain disorders.
- Structural TN e.g., due to vascular compression, posterior fossa tumors, central demyelination, …etc.
- Patients exposed to previous radiofrequency procedures, as this may impair the nerve response to current PRF.
- Patients who refused to participate in the study.
Where it is running
- Alexandria University Faculty of Medicine — Alexandria, Egypt (enrolling)
- Cairo University Kasr Alainy Faculty of Medicine — Cairo, Egypt (enrolling)
Full record on ClinicalTrials.gov
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