A Study to Evaluate the Effect of Food on Nemtabrutinib (MK-1026) in Healthy Participants (MK-1026-016)

Completed · Phase 1

Conditions studied: Healthy

In brief

The goal of the study is to learn what happens to levels of nemtabrutinib in a healthy person's body over time. Researchers will compare what happens to nemtabrutinib in the body when it is given under fasted (on an empty stomach) and fed (after a high-fat meal) conditions.

Key facts

Study ID

NCT06772805

Run by

Merck Sharp & Dohme LLC

People needed

18

Starts

2023-07-24

Expected to finish

2023-12-12

Last updated by the study team

2025-01-14

Who can join

Age: 18 and older, up to 45. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Inclusion criteria include, but are not limited to:
• Is in good health based on medical history, physical examination, vital sign measurements, and electrocardiograms (ECGs) performed before randomization
• Has a body mass index (BMI) 18 to 32 kg/m\^2 (inclusive)

You may not qualify if…

• Exclusion criteria include, but are not limited to:
• Has a history of clinically significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases
• Has a history of cancer (malignancy)

Where it is running

• Labcorp Clinical Research Unit Inc. (Site 0001) — Honolulu, Hawaii, United States

Full record on ClinicalTrials.gov

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