Taiwan Post-Stroke Disability Study

Recruiting now

Conditions studied: Stroke, Dementia, Epilepsy, Depression

In brief

Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range of disabilities in areas such as motor function, swallowing, cognition, depression, and epilepsy. This study will investigate these disabilities by enrolling 2,000 acute stroke patients (both ischemic and hemorrhagic) from 10 medical centers across Taiwan. Data will be collected at three key points: at enrollment, three months, and twelve months post-stroke, using surveys, assessments, imaging, and blood samples. The aim is to examine the prevalence, risk factors, and long-term changes of post-stroke disabilities, ultimately seeking ways to reduce the health burden of stroke in Taiwan.

Key facts

Study ID

NCT06772194

Run by

National Taiwan University Hospital

People needed

2000

Starts

2024-10-21

Expected to finish

2028-09-30

Last updated by the study team

2025-05-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ischemic stroke confirmed by MRI, or hemorrhagic stroke diagnosed by CT or MRI.
• Age ≥ 18 years.
• Pre-stroke modified Rankin Scale (mRS) score of 0, 1, or 2.
• Post-stroke mRS score of 0, 1, 2, 3, or 4 at enrollment.
• Able to undergo cognitive function screening and other scale assessments within 30 days post-stroke.

You may not qualify if…

• Transient ischemic stroke and subarachnoid hemorrhage.
• Clear and severe psychiatric or emotional disorders before the stroke, including schizophrenia, major depressive disorder, and bipolar disorder.
• History of clinical stroke within three months prior to enrollment.
• Unable to communicate or cooperate for assessments due to severe aphasia.
• Severe dementia prior to the stroke.
• Pre-stroke modified Rankin Scale (mRS) score ≥ 3.
• Post-stroke mRS score of 5 at enrollment.
• History of cancer with an expected life expectancy of less than one year.
• Expected life expectancy of less than one year due to other medical conditions.
• Anticipated inability to complete a one-year follow-up.
• Other situations deemed unsuitable for enrollment by the clinical investigator.

Where it is running

• National Taiwan University Hospital, Taipei, — Taipei, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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