Longitudinal Study of the GLUcagon REsponse to Hypoglycemia in Children and Adolescents With New-onset Type 1 DIAbetes

Recruiting now · Not applicable

Conditions studied: Severe Hypoglycemia, Type1diabetes

In brief

The GLUREDIA study investigates the counter-regulatory response (CRR) during hypoglycemia in children with type 1 diabetes (T1D). Hypoglycemia can lead to severe symptoms, but is normally counteracted by CRR, corresponding to the secretion of hormones to maintain normoglycemia. Hypoglycemia is common in T1DM but some patients develop severe hypoglycemia as a result of CRR dysfunction. Despite several studies in adults, the presence of CRR dysfunction remains unpredictable and not well understood. The objective of GLUREDIA is therefore to describe and predict the evolution of CRR in children with T1DM.

Key facts

Study ID
NCT06770621
Run by
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
People needed
1000
Starts
2022-05-25
Expected to finish
2025-10-25
Last updated by the study team
2025-01-13

Who can join

Age: 2 and older, up to 30. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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