Vitiligo, New Treatment and Serum s100B

Recruiting now · Phase 2/Phase 3

Conditions studied: Vitiligo, Generalized

In brief

vitiligo is an autoimmune depigmenting skin disorder characterized by milky white macules or patches, with 2% worldwide prevalence. Vitiligo has unexpected course that significantly influences on patient's quality of life and self-esteem. Multiple medications have been introduced for vitiligo treatment, in this study we work on one of systemic JAK inhibitors

Key facts

Study ID

NCT06768840

Run by

South Valley University

People needed

50

Starts

2024-10-02

Expected to finish

2025-10-01

Last updated by the study team

2025-01-10

Who can join

Age: 10 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• active generalized vitiligo patients with body surface area involved >5% excluding hands and feet
• no systemic treatment for vitiligo for the last 3 months or topical treatment received for the last 4 weeks.

You may not qualify if…

• acrofacial, acral, segmental or mucosal vitiligo
• patients on another immunosuppressive agent
• patients have other skin conditions (psoriasis, SLE, alopecia areata) that would interfere with evaluations of the effect of study medication on vitiligo.
• patients who suffered from systemic diseases affecting S100B (e.g. Subarachnoid hemorrhage, Alzheimer disease and inflammatory diseases) or from other dermatological diseases affecting S100B level (e.g. malignant melanoma)
• Patients immunocompromised, uncontrolled arterial hypertension, clinically serious viral, bacterial, fungal, or parasitic infection, anemia, history of thromboembolic event, cardiovascular, respiratory, hepatic, gastrointestinal, endocrine, hematological, lymphoproliferative disease, neurological, or neuropsychiatric disorders or any other serious and/or unstable illness.
• Pregnancy and lactation.

Where it is running

• Qena university hospital, Qena faculty of medicine — Qina, Egypt (enrolling)

Full record on ClinicalTrials.gov

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