Comparison of MIST With PRF and GBT With PRF in the Treatment of Intrabony Periodontal Defect. A Prospective RCT
Recruiting now · Not applicable
Conditions studied: Intrabony Periodontal Defect
In brief
The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a MIST procedure combined with PRF, or GBT combined with PRF. Clinical, radiological evaluation of the regenerative surgical method and the GBT non-surgical therapy in solitaire deep intrabony periodontal defect.
Key facts
- Study ID
- NCT06768424
- Run by
- Semmelweis University
- People needed
- 36
- Starts
- 2023-12-20
- Expected to finish
- 2027-12-20
- Last updated by the study team
- 2026-04-28
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- solitaire intrabony periodontal defect at least 4 mm
You may not qualify if…
- Periodontitis with intrabony defect (Intrabony component ≥ 4mm, defect radiological angulation > 25°,
- The patient is able to comply with the study -related procedures (i.e. good level of oral hygiene, follow-up procedures).
- Patients must not be heavy smokers (<5 cigarettes/day).
- furcation involvement
- Full mouth plaque and bleeding scores (FMPS and FMBS) of <15% (O'Leary et al. 1972).
- The patient is able to fully understand the nature of the study, signed informed consent.
Where it is running
- Semmelweis University Department of Periodontology — Budapest, Budapest, Hungary (enrolling)
Full record on ClinicalTrials.gov
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