Effects of Low-Sodium Salt on Death, HF Hospitalization/ Emergency Department Visits and Quality of Life in HF Patients
Recruiting now · Not applicable
Conditions studied: Heart Failure, Dietary Sodium Intake
In brief
This study aims to investigate whether using a low-sodium substitute salt can help improve outcomes for patients with heart failure. Specifically, it will examine if the low-sodium substitute salt can reduce death rates, hospital readmissions, and emergency visits, as well as improve the quality of life for these patients.
Key facts
- Study ID
- NCT06764225
- Run by
- Heart Health Research Center
- People needed
- 1301
- Starts
- 2025-04-03
- Expected to finish
- 2027-04-30
- Last updated by the study team
- 2025-05-21
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aged between 18 and 75 years;
- Hospitalized due to heart failure in the past year;
- NYHA functional class II-III;
- Echocardiographic evidence of LVEF < 40% within the past 6 months;
- Receiving guideline-directed medical therapy for heart failure;
- Stable heart failure status, defined as heart failure stability for more than 4 weeks, with no increase in diuretic dose within the past 4 weeks;
- Having a primary caregiver and frequently dining together at home;
- Consuming commercially processed food no more than once a week;
- Providing written informed consent.
You may not qualify if…
- End-stage heart failure;
- Hospitalization due to cardiovascular causes within the past month;
- Uncorrected hyponatremia (Na < 130 mmol/L);
- Dialysis-dependent patients, or eGFR < 20 mL/min/1.73m²;
- Uncontrolled hyperglycemia, with fasting blood glucose > 16 mmol/L;
- Malignant cancer patients with a life expectancy of less than 1 year;
- Conditions that, in the investigator's opinion, may interfere with adherence to the protocol, such as habitual reliance on takeout meals or dining at company cafeterias;
- Planned hospitalization during the study period;
- Unexplained weight loss greater than 5 kg in the past year;
- The subject or family members have concerns about using the salt substitute in this study, or are planning for pregnancy, pregnant, or breastfeeding;
- Another family member is already participating in this study;
- The subject or family members are participating in other interventional clinical trials.
Where it is running
- Anzhen Hospital, Capital Medical University — Beijing, Beijing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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