Comparison Between Fentanyl and Dexmedetomidine As Adjuvant to Bupivacaine in Combined IPACK and Adductor Canal Block for Postoperative Analgesia After Knee Surgeries

Recruiting now · Not applicable

Conditions studied: Analgesia, Postoperative

In brief

This study will be undertaken to compare the analgesic effects of of fentanyl versus dexmedetomidine as adjuvant to bupivacaine in combined IPACK and ACB for pain management after total knee arthroplasty.

Key facts

Study ID

NCT06759116

Run by

Zagazig University

People needed

111

Starts

2025-01-10

Expected to finish

2025-08-10

Last updated by the study team

2025-01-14

Who can join

Age: 21 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 1 - Patient acceptance 2. Cooperative patients 3. Age: ≥21 and 85< years' old 4. Sex: both sexes (males or females). 5. Physical status: ASA Ι \& II\& Ш. 6. Body Mass Index (BMI): ≤ 35 kg/m2. 7. Type of operation: elective unilateral knee surgeries (TKA, ACL, knee arthroscopy)

You may not qualify if…

• . Patient with any contraindications of regional blocks (as coagulopathy or local infection at injection site) 2. Patients with known history of allergy to the study drugs (bupivacaine, dexmedetomidine and fentanyl).
• Advanced hepatic, renal, cardiovascular, neurologic and respiratory diseases.
• Chronic opioid use (more than 3 months or daily oral morphine > 5 mg /day for 1 month)

Where it is running

• faculty of human medicine, Zagazig university hospitals — El Sharkia, Egypt (enrolling)

Full record on ClinicalTrials.gov

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