Rehabilitation Strategies for Social Participation in Chronic Stroke Survivors

Recruiting now · Not applicable

Conditions studied: Stroke, Chronic Phase of Disease

In brief

The goal of this clinical trial is to test a new rehabilitation program, combining acceptance and commitment therapy with strategy training (ACES), to help people resume social participation after stroke and live in the community. Investigators will also compare the changes in social participation and psychological flexibility from baseline to follow-up at one-month after rehabilitation to see if participants who receive ACES report clinically meaningful improvements (Cohen's d=0.2 or greater) compared to the existing rehabilitation program using strategy training alone (START). Participants will: * complete testing to see if they are eligible for the study. If qualified, complete testing to understand how the stroke has affected their daily life * be randomized to receive either ACES or START rehabilitation program for 10 sessions at their home * repeat part of the tests at the end of the intervention and one month after

Key facts

Study ID

NCT06758505

Run by

University of Pittsburgh

People needed

54

Starts

2025-09-29

Expected to finish

2027-06-01

Last updated by the study team

2025-10-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• primary diagnosis of chronic stroke, ≥6 months post onset,
• ≥18 years old,
• community-dwelling (i.e., living in a residential setting in the community),
• restrictions in social participation, indicated by Activity Card Sort (<80% of pre-stroke activities)

You may not qualify if…

• progressive neurological diagnosis (e.g., dementia, Parkinson's disease, multiple sclerosis, or brain tumor) reported by participants or proxy,
• inability to provide written informed consent,
• severe aphasia (score 0 or 1 on the Boston Diagnostic Aphasia Examination 3rd Edition Severity Rating Scale),
• currently undergoing stroke rehabilitation or mental health intervention (but participation in maintenance sessions, self-help groups, or couples therapy is permitted),
• major depressive disorder, indicated by PRIME-MD, unless undergoing treatment for at least 4 weeks and are released to participate by their physician or counselor
• bipolar or psychotic disorder, indicated by PRIME-MD, or
• substance use disorder within 3 months, indicated by Mini-International Neuropsychiatric Interview

Where it is running

• University of Pittsburgh — Pittsburgh, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.