Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects

Available (expanded access)

Conditions studied: Biochemical Markers

In brief

The effect of physical activity on serum cartilage biomarkers is largely unknown. This study is critical to increase our knowledge of the physiological cartilage response to activities of daily living and dynamic tasks by focusing on healthy recreationally active individuals, thus improving our understanding of the complex relationship between cartilage health and the loading that occurs during different types of loading.

Key facts

Study ID

NCT06757699

Run by

Kocaeli University

Last updated by the study team

2026-06-10

Who can join

Age: 20 and older, up to 35. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Healthy male volunteers between the ages of 20-35
• Those who do physical activity for at least 30 minutes two to three days a week
• 17 healthy male individuals without any health problems will be included.

You may not qualify if…

• Those with acute or chronic injuries in their lower extremities
• Those with musculoskeletal disorders in their lower extremities
• Those who have undergone hip and/or knee surgery
• Those with cardio-pulmonary problems that prevent them from exercising

Where it is running

• Kocaeli University Faculty of Medicine Hospital — Kocaeli, Turkey (Türkiye)
• Sakarya University Applied Sciences Physiotherapy and Rehabilitation Application and Research Center — Sakarya, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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