Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).
Recruiting now · Not applicable
Conditions studied: Alveolar Socket Preservation
In brief
The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used. Autogenous dentin, taken from the patient, supports healing and bone regrowth. Platelet-rich fibrin (PRF), made from the patient's blood, enhances healing and bone density by releasing growth factors. A new technique combining L-PRF with albumin creates a stable healing membrane that provides a steady release of growth factors. Overall, these methods improve recovery after tooth extractions and prepare sites for future dental work.
Key facts
- Study ID
- NCT06757218
- Run by
- Kafrelsheikh University
- People needed
- 60
- Starts
- 2025-06-01
- Expected to finish
- 2026-08-30
- Last updated by the study team
- 2025-07-10
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Medically free patients.
- Adult patients above 18 Years to 60 Years.
- Non-restorable tooth indicated for extraction.
- Posterior mandibular teeth.
- Inactive infection related to the tooth.
- Cooperative patients.
You may not qualify if…
- Presence of any systemic disease that could influence the outcome of the therapy.
- Presence of any risk factor (smoker, pregnant and lactating patients).
- Patients with bone diseases.
- Patients with poor oral hygiene.
Where it is running
- Kaferelsheikh University — Kafr ash Shaykh, Kafrelsheikh, Egypt (enrolling)
Full record on ClinicalTrials.gov
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