Comparison of High Flow Nasal Oxygen and Nasal Cannula in Burn Patients Under Sedation

Recruiting now

Conditions studied: Burn Injury, Hypoxia, Sedation

In brief

Burn-related pain is severe and often difficult to manage. Burn patients often require high doses of opioids and anxiolytics. Anesthetic agents used during sedation such as benzodiazepines, propofol and opioids can cause respiratory depression, predisposing patients to hypoventilation and hypoxemia due to airway obstruction. Oxygen is administered to patients with a standard nasal cannula during sedation. High Flow Nasal Oxygen (HFNO) helps to improve the oxygenation of patients with respiratory distress by delivering high flow humidified oxygen through the nasal cannula at a high rate of up to 40-70 liters per minute. The aim of this study was to compare the effects of HFNO and nasal oxygen therapy in preventing hypoxemia in deeply sedated burn patients.

Key facts

Study ID

NCT06756906

Run by

Ankara City Hospital Bilkent

People needed

70

Starts

2024-07-15

Expected to finish

2025-02-10

Last updated by the study team

2025-01-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Intubation
• Tracheostomies
• Need for oxygen therapy due to preexisting disease
• Pregnancy

Where it is running

• Ankara Bilkent City Hospital — Ankara, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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