Evaluation of Chronic Liver Disease Condition and Transplant Prognosis Assisted by Eye Biological Parameters
Recruiting now
Conditions studied: Diagnostic Techniques, Ophthalmological, Liver Transplantation, Liver Cirrhoses
In brief
This study investigates the correlation between ocular biological characteristics and overall conditions before and after liver transplantation by collecting ocular biological characteristics. Explore whether it is possible to construct a clinical prediction model for liver transplantation by incorporating ocular biometric features, in order to optimize disease management before and after liver transplantation.
Key facts
- Study ID
- NCT06756009
- Run by
- Zhongshan Ophthalmic Center, Sun Yat-sen University
- People needed
- 500
- Starts
- 2022-03-01
- Expected to finish
- 2026-12-30
- Last updated by the study team
- 2025-01-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age greater than or equal to 18 years old;
- Late stage liver disease patients waiting for liver transplantation treatment, as well as patients with varying degrees of cirrhosis;
- Can collect complete basic demographic information, liver function blood test indicators, liver pathology and imaging examination results;
- Can cooperate with eye OCT, OCTA and other examinations, and obtain qualified examination parameters;
- Voluntarily follow the clinical trial protocol and sign the informed consent form.
You may not qualify if…
- History of other organ transplant surgeries;
- History of intraocular laser treatment, medication injection, and surgery;
- History of high myopia, glaucoma, and retinal choroidal related eye diseases;
- History of major systemic diseases other than liver disease;
- Individuals whose overall body and eye conditions cannot cooperate with eye examinations.
Where it is running
- Zhongshan Ophthalmic Center, Sun Yat-sen University — Guangzhou, Guangdong, China (enrolling)
Full record on ClinicalTrials.gov
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