Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy

Recruiting now · Phase 4

Conditions studied: Visceral Pain, Analgesia, Opioid Use, Postoperative Nausea, Postoperative Vomiting

In brief

This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical manifestations, reduce analgesic requirements, and lower readmission rates, thereby facilitating recovery.

Key facts

Study ID

NCT06753500

Run by

Universidad Simón Bolívar

People needed

60

Starts

2025-01-15

Expected to finish

2025-11-04

Last updated by the study team

2025-01-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Elective or emergency laparoscopic cholecystectomy for cholelithiasis with or without cholecystitis.

You may not qualify if…

• Associated biliary pathologies (e.g., biliary pancreatitis, cholangitis).
• Additional procedures, such as formal bile duct exploration. Conversion to an open approach
• Anesthesia or Surgical complications that require intensive care unit
• Allergies to local anesthetics

Where it is running

• Clinica Portoazul — Barranquilla, Atlantivo, Colombia (enrolling)
• clinica Iberoamerica — Barranquilla, Atlántico, Colombia (enrolling)

Full record on ClinicalTrials.gov

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