Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery

Recruiting now · Not applicable

Conditions studied: Postoperative Acute Kidney Injury

In brief

This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).

Key facts

Study ID

NCT06753409

Run by

Assiut University

People needed

162

Starts

2025-02-01

Expected to finish

2027-01-01

Last updated by the study team

2025-02-04

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients scheduled for major abdominal surgery lasting more than 2 hours under general anesthesia.
• American Society of Anesthesiologists Physical Status (ASA) score I-III.
• Age range of 18-70 years.
• Both male and female patients.

You may not qualify if…

• Emergency surgeries.
• Uncontrolled hypertension (systolic blood pressure >150 mm Hg) despite medication.
• Recent acute cardiovascular events, including heart failure or acute coronary syndrome.
• Chronic kidney disease with a glomerular filtration rate <30 ml/min/1.73 m² or requiring renal replacement therapy.
• Severe hepatic failure (ASAT/ALAT >2N, elevated bilirubin, or PT <50%).
• Preoperative sepsis or septic shock.
• Pregnancy.
• Patient refusal to participate in the study.

Where it is running

• Assiut University Hospitals — Asyut, Egypt (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.