DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
Recruiting now · Phase 2
Conditions studied: Cancer of the Breast, Chemotherapy-induced Neuropathy
In brief
Up to 80% of breast cancer survivors experience chemotherapy-induced neuropathy that impairs quality of life and increases fall risk long into survivorship, yet treatment options for neuropathy remain limited. The successful treatment will target neurophysiologic mechanisms for restoring function while addressing patient-reported symptoms and participation in treatment. Toward this end, the investigators propose to study a noninvasive, social sensorimotor intervention - Adapted Argentine Tango - which targets motor control restoration, symptom alleviation, and treatment participation in concert.
Key facts
- Study ID
- NCT06749210
- Run by
- Ohio State University Comprehensive Cancer Center
- People needed
- 140
- Starts
- 2025-02-19
- Expected to finish
- 2029-08-15
- Last updated by the study team
- 2025-11-05
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Breast Cancer (BC) diagnosis of Stage I-IV including metastatic disease
- completed taxane-based chemotherapy for BC at least 3 months ago (no limit on how long ago)
- symptomatic for chemotherapy-induced neuropathy (self-report)
- postural control score that indicates potential fall-risk
- able to understand and comply with directions associated with testing and study treatments
You may not qualify if…
- pre-existing vestibular dysfunction
- poorly controlled diabetes (hgA1C>=8)
- non-ambulatory (assistive and prosthetic devices allowed)
- hearing impairment resulting in less than 10% hearing bilaterally
- contraindication to participate in the experimental physical activity per the treating oncologist due to additional condition (e.g., herniated disc, unstable bone metastases)
- currently in activity-based therapy (e.g., physical therapy, occupational therapy). May enroll if still meet eligibility criteria once activity-based therapy is complete.
Where it is running
- Yale University — New Haven, Connecticut, United States (enrolling)
- The Ohio State University — Columbus, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
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