Research on Circulation Management Strategy Based on Oxygen Metabolism Balance After CHD Surgery

Enrolling by invitation · Not applicable

Conditions studied: Congenital Heart Disease (CHD), Cardiopulmonary Bypass, Children, Oxygen Delivery, Oxygen Consumption, Oxygen Saturation, Goal-directed Therapy

In brief

The objective is to investigate a goal-oriented postoperative circulation management strategy centered on "oxygen metabolism balance". This strategy is independent of the absolute metrics of oxygen supply and consumption, and aims to enhance oxygen consumption and uptake within the critical "golden 8 hours" following pediatric cardiopulmonary bypass, thereby preventing severe hypotension, cardiopulmonary arrest, and other adverse events.

Key facts

Study ID

NCT06747546

Run by

Children's Hospital of Fudan University

People needed

300

Starts

2025-01-01

Expected to finish

2027-12-31

Last updated by the study team

2026-03-16

Who can join

Age: 0 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 1.Body weight > 2.5kg;
• 2.Preoperative oxygen saturation >80%;
• 3.Biventricular radical surgery with cardiopulmonary bypass.

You may not qualify if…

• 1. Complicated with functional single ventricle and atrial isomerism;
• 2.Complicated with liver, kidney, lung, brain and other vital organ diseases;
• 3.History of rescue before operation;
• 4.Palliative surgery;
• 5.Residual deformities that significantly affected hemodynamics after operation;
• 6.Guardians did not provide the bundle of informed consent.

Where it is running

• Children's Hospital of Fudan University — Minhang, Shanghai Municipality, China

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.