Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders

Recruiting now

Conditions studied: Lipid Disorders

In brief

This study looks at how lipoproteins, which are particles in the blood that transport cholesterol, influence heart and blood vessel health. Beyond just their levels, the way these particles function plays a key role in preventing or contributing to disease. In some conditions, like high cholesterol or diabetes, lipoproteins may not work properly, increasing the risk of clogged arteries and other complications. The investigators aim to study these changes in people with lipid disorders to better understand their impact on blood health and to find new ways to prevent and treat heart disease.

Key facts

Study ID

NCT06747000

Run by

The Miriam Hospital

People needed

80

Starts

2024-07-18

Expected to finish

2029-07-18

Last updated by the study team

2025-10-01

Who can join

Age: 18 and older, up to 69. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy volunteers
• Abnormalities in lipid panels
• Able to provide informed consent
• Between the age of 18 and 69

You may not qualify if…

• Drug or alcohol abuse within 6 months or significant mental/psychological impairment
• Current smokers
• Subjects with known bleeding disorders (for example, hemophilia)
• Subjects requiring regular transfusions for any reason
• No ethnic/racial groups will be excluded

Where it is running

• Brown University Health Lipid Clinic — East Providence, Rhode Island, United States (enrolling)
• Cardiovascular Research Center — Providence, Rhode Island, United States (enrolling)

Full record on ClinicalTrials.gov

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