Screening and Molecular Diagnosis-based Individualized Precision Management of Monogenic Diabetes
Recruiting now · Not applicable
Conditions studied: Monogenic Diabetes
In brief
The goal of this observational study is to establish a registry, screening, and individualized management platform for patients with monogenic diabetes mellitus(MDM) using internet-based and mobile application software. The main questions it aims to answer are: * What are the genetic mutations causing MDM in China (genetic landscape)? * How effective and safe is the individualized, molecular-diagnosis-based management platform for MDM in improving patient outcomes? Participants will: * Register in the MDM platform via mobile app or internet-based software * Undergo genetic screening for MDM diagnosis * Participate in follow-up visits for individualized management and monitoring of blood glucose control and outcomes
Key facts
- Study ID
- NCT06746610
- Run by
- Tianjin Medical University General Hospital
- People needed
- 2000
- Starts
- 2022-08-01
- Expected to finish
- 2027-07-31
- Last updated by the study team
- 2024-12-24
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diabetes patients who developed before 25 years old; Or they were diagnosed with diabetes before the age of 35, and two or more immediate relatives were diagnosed with diabetes before the age of 45;
- Body mass index (BMI) at diagnosis < 28 kg/m2;
- Anti glutamic acid decarboxylase antibody (GAD Ab), anti islet cell antibody (ICA Ab), and anti insulin autoantibody (IAA Ab) were all negative;
You may not qualify if…
- Secondary diabetes patients with other endocrine diseases, such as hyperthyroidism or hypothyroidism, hyperparathyroidism or hypothyroidism, acromegaly, Cushing's syndrome, autoimmune multiple endocrine diseases, etc.;
- Systemic use of corticosteroids, immunosuppressants, and other drugs within the past 6 months;
- Patients with malignant tumors.
Where it is running
- Tianjin Medical University General Hospital — Tianjin, China (enrolling)
Full record on ClinicalTrials.gov
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