Evaluation of the Reproducibility of the Automated Measurement of the Extent of ILD on Chest CT

Recruiting now · Not applicable

Conditions studied: Interstitial Lung Disease

In brief

In interstitial lung disease (ILD), the extent of ILD on chest computed tomography (CT) is recognized as an important prognostic factor. Automated tools are now available to quantify ILD, but there is a lack of data on the reproducibility of this measurement and therefore its accuracy. Therefore, the purpose of this study is to evaluate the variability of automated ILD quantification on chest CT. Reproducibility will be assessed by repeating chest CT scans and using different tools to measure the extent of disease.

Key facts

Study ID

NCT06743022

Run by

Assistance Publique - Hôpitaux de Paris

People needed

150

Starts

2025-06-24

Expected to finish

2026-09-01

Last updated by the study team

2026-01-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Known interstitial lung disease as part of idiopathic pulmonary fibrosis or connective tissue disease
• Followed in one of the participating hospitals
• Requiring a chest CT as part of a scheduled assessment
• Affiliated to a French national social security
• Informed consent

You may not qualify if…

• Acute exacerbation of ILD
• Pregnancy
• Inability to hold an apnea for 10 seconds
• Patients in the exclusion period after a previous research
• Need for additional procubitus or expiratory images

Where it is running

• APHP - Bichat hospital - Radiology — Paris, IDF, France (enrolling)
• APHP - Bichat hospital - Rheumatology — Paris, IDF, France (enrolling)
• APHP - Cochin Hospital - Internal medicine — Paris, IDF, France (enrolling)
• APHP - Cochin Hospital - Pneumology — Paris, IDF, France (enrolling)
• APHP - Cochin Hospital - Radiology — Paris, IDF, France (enrolling)
• APHP - Bichat Hospital - Pneumology — Paris, IDF, France (enrolling)

Full record on ClinicalTrials.gov

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