Carbohydrates and Running Performance

Completed · Not applicable

Conditions studied: Nutrition, Healthy

In brief

Carbohydrates serve as the body's primary energy source during intense exercise, and consuming carbohydrates during exercise has been shown to improve exercise performance. Previous research has shown that the presence of carbohydrates in the mouth activates sweet taste receptors on the tongue, which signal the brain to increase neural activation in areas associated with motor functioning, sensory perception, and reward centers during exercise through this CPR. The primary objective of this intervention is to establish how carbohydrates delivered in different forms (MR versus dissolvable strip (DS)) affect running performance during a 12.8km running TT.

Key facts

Study ID

NCT06742398

Run by

University of Georgia

People needed

36

Starts

2024-02-16

Expected to finish

2025-06-01

Last updated by the study team

2025-07-24

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18-45 years old
• Male or Female
• Normal body mass index (BMI) between 18.0-24.9kg/m2
• All subjects will be endurance-trained athletes who participate in training on a regular basis (≥4 sessions per week for at least 1 hour per session of aerobic/endurance exercise (such as running, cycling, or swimming)
• Women will be tested only during the follicular phase of their menstrual cycle (days 2-9) to control for any fluctuation in hormones
• Individuals aged 35 or older must pass the Physical Activity Readiness Questionnaire (PARQ2)

You may not qualify if…

• Anyone eating a low carbohydrate diet (such as The Zone™ Diet or Atkins™ Diet)
• Changes in current exercise program
• Chronic diseases (including but not limited to type II diabetes, hypertension, hypotension, hyperthyroidism, cardiovascular disease, and cancer)
• Medications that could alter metabolic rate or hydration status
• Supplement use other than fish oil or vitamin/mineral supplements
• Nicotine use
• Pregnancy or nursing
• Donation of blood in the 20 days prior to testing
• A failing result on the Physical Activity Readiness Questionnaire (PARQ2) for those aged 35 or older
• Allergy to red food dye FD\&C Red No. 40

Where it is running

• University of Georgia — Athens, Georgia, United States

Full record on ClinicalTrials.gov

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