Difference Between Monofilament Versus Multifilament Suture Material in Isthmocele Formation

Recruiting now · Not applicable

Conditions studied: Uterine Scar

In brief

This thesis conducts the effect of using different suture materials on the development of uterine scar niche after cesarean section. The difference between monofilament and multifilament sutures and the special properties of each one . The primary outcome of the study is to know which material conducts more scar niche formation . Secondary outcomes are the extent of blood loss , the need of extra hemostatic sutures

Key facts

Study ID

NCT06741371

Run by

Ain Shams Maternity Hospital

People needed

140

Starts

2024-01-01

Expected to finish

2025-03-01

Last updated by the study team

2024-12-19

Who can join

Age: 20 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Age: 20-45 years old
• Singleton pregnancy.
• Gestational age between 37 completed weeks to 42 weeks.
• Patients undergoing elective primary caesarean section

You may not qualify if…

• History of uterine surgery (e.g. hysterotomy, myomectomy, perforation, caesarean section). (to be able to differentiate between the recent CS scar and the old scar)
• Abnormal placental invasion (placenta previa and accrete ) ( more liable to undergo Cesarean hysterectomy)
• Uterine anomalies (e.g., septum, Mullerian anomalies or fibroids). (may be localized at the suture line and therefore affect the scar)
• Drugs intake that affects bleeding or tissue healing e.g., anti-coagulants, immunosuppressive drugs and chronic use of steroids (more than 14 days pre-operative)
• Any medical Co-morbidity (diabetes mellitus, Hypertension and Thyroid abnormalities) (more liable to affect the healing)

Where it is running

• Faculty of medicine — Cairo, Abbasya, Egypt (enrolling)

Full record on ClinicalTrials.gov

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