A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage)

Running, not enrolling · Phase 3 · Has a placebo group

Conditions studied: Generalized Anxiety Disorder

In brief

A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating DT120 Compared to Placebo in Generalized Anxiety Disorder - Voyage

Key facts

Study ID

NCT06741228

Run by

Definium Therapeutics US, Inc.

People needed

214

Starts

2024-12-11

Expected to finish

2026-11-01

Last updated by the study team

2026-06-22

Who can join

Age: 18 and older, up to 74. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of GAD per DSM-5
• Male or female aged 18 to 74
• HAM-A Total Score ≥20

You may not qualify if…

• Certain psychiatric disorders (other than generalized anxiety disorder)
• First degree relative with or lifetime history of a psychotic disorder or bipolar disorder
• Current diagnosis of alcohol or substance use disorder (excluding nicotine and caffeine)
• Any clinically significant unstable illness

Where it is running

• Lighthouse Psychiatry — Gilbert, Arizona, United States
• Scottsdale Research Institute — Scottsdale, Arizona, United States
• Kadima Neuropsychiatry Institute — La Jolla, California, United States
• UCSF Department of Neurology — San Francisco, California, United States
• Psychedelic Science Institute — Santa Monica, California, United States
• Mountain View — Denver, Colorado, United States
• Clinical Neuroscience Solutions Inc. — Jacksonville, Florida, United States
• Segal Trials — Lauderhill, Florida, United States
• Atlanta Center for Medical Research — Atlanta, Georgia, United States
• iResearch Atlanta — Decatur, Georgia, United States
• CenExel iResearch, LLC — Savannah, Georgia, United States
• Uptown Research Institute — Chicago, Illinois, United States
• Adams Clinical Boston — Boston, Massachusetts, United States
• Adams Clinical Watertown — Watertown, Massachusetts, United States
• Hassman Research Institute — Marlton, New Jersey, United States
• Spectrum Neuroscience and Treatment Institute — New York, New York, United States
• Adams Clinical Harlem — New York, New York, United States
• New York State Psychiatric Institute (NYSPI) — New York, New York, United States
• Adams Clinical Bronx — The Bronx, New York, United States
• Cleveland Clinic Lutheran Hospital — Cleveland, Ohio, United States
• Summit Headlands LLC — Portland, Oregon, United States
• Scranton Medical Institute — Moosic, Pennsylvania, United States
• Adams Clinical Philadelphia — Philadelphia, Pennsylvania, United States
• Coastal Carolina Research Center — North Charleston, South Carolina, United States
• Clinical Neuroscience Solutions, Inc. — Memphis, Tennessee, United States

Full record on ClinicalTrials.gov

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