Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Starting soon · Not applicable · Has a placebo group
Conditions studied: Obesity, Postoperative Pain, Bariatric Surgery
In brief
This randomized controlled trial aims to compare the analgesic efficacy of dexmedetomidine infusion versus low-dose ketamine infusion as adjuvants in bariatric surgery. The study includes 90 patients undergoing bariatric surgery at Menoufia University Hospital, randomized into three groups: dexmedetomidine, ketamine, and control (placebo). Primary outcomes include total morphine consumption intra- and post-operatively. Secondary outcomes include postoperative pain scores, total analgesic consumption, time to first analgesic request, hemodynamic parameters, and patient satisfaction. This study seeks to explore safer, more effective pain management strategies to minimize opioid use in bariatric surgery patients.
Key facts
- Study ID
- NCT06738043
- Run by
- Tanta University
- People needed
- 90
- Starts
- 2026-04-20
- Expected to finish
- 2027-04-20
- Last updated by the study team
- 2026-04-09
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged 18-60 years.
- Both sexes.
- Body mass index (BMI) > 35 kg/m², scheduled for bariatric surgery.
- American Society of Anesthesiologists (ASA) physical status I-II.
You may not qualify if…
- History of hypersensitivity to dexmedetomidine or ketamine.
- History of substance abuse or chronic opioid use.
- American Society of Anesthesiologists (ASA) physical status III or IV.
- Severe hepatic or renal impairment.
- Cardiopulmonary disorders.
- Severe diabetes mellitus.
- Psychiatric disorders, seizures, uncontrolled hypertension (systolic ≥ 140 mmHg or diastolic ≥ 90 mmHg), or heart block.
Full record on ClinicalTrials.gov
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