Transcranial Stimulation Combined With Auditory Training

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Difficulties Understanding Speech in Noise

In brief

The goal of this clinical trial is to learn if non-invasive brain stimulation (called transcranial stimulation) can enhance the benefits from auditory training in people who struggle to understand one talker when many people are talking at the same time. The main questions it aims to answer are: * Does transcranial stimulation improve speech-on-speech understanding in people who struggle with this task? * Does transcranial stimulation enhance the benefits of a commercially available auditory training program? Researchers will compare transcranial stimulation to sham stimulation (no stimulation is applied during the listening task). Participants will: * Receive login information to an online auditory training program to complete at home over 2 weeks * Visit the laboratory 4 times to receive transcranial stimulation while listening to speech-on-speech: once before at-home training, two times during the at-home training period, and once after at-home training has ended

Key facts

Study ID

NCT06738030

Run by

Boston University Charles River Campus

People needed

94

Starts

2025-11-07

Expected to finish

2027-03-01

Last updated by the study team

2026-07-29

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 50 years of age or older
• Audiometric thresholds that do not exceed 90 dB HL at any frequency from 250-6000 Hz
• Able to provide informed consent and understand experimental instructions
• Able to read print on a computer screen
• Difficulty with speech-on-speech understanding
• Access to computer or mobile phone with access to internet that can play sound (for the at-home training)

You may not qualify if…

• Non-native speakers of English
• History of skull fracture, scalp tissue damage, metallic implants around the head, seizures, neurological disorders, or traumatic brain injury, current or suspected pregnancy

Where it is running

• Communication Neuroscience Research Lab at Boston University — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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