Relationship Between Pulse Pressure and Stroke Volume in the Critically Ill Patients: The ANDROMEDA-PEGASUS Study

Recruiting now

Conditions studied: Critical Illness

In brief

The goal of this study is to assess the predictive capacity of pulse pressure to estimate stroke volume, as assessed by bedside echocardiography in critically ill patients. We hypothesize that pulse pressure will be able to adequately detect low values of stroke volume, and to track changes of stroke volume during commonly used dynamic cardiovascular interventions. Pulse pressure transduced from an arterial line will be measured simultaneously with left ventricular outflow tract velocity time integral in a broad range of critically ill patients. Ancillary clinical, hemodynamic and echocardiographic data will also be registered.

Key facts

Study ID

NCT06737614

Run by

Pontificia Universidad Catolica de Chile

People needed

1500

Starts

2025-05-01

Expected to finish

2026-01-30

Last updated by the study team

2025-05-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years
• Admitted to ICU
• Functioning arterial line in place

You may not qualify if…

• Pregnancy
• Inadequate arterial line transduction (see below)
• Refusal of consent
• Patient who requires extracorporeal circulation

Where it is running

• Hospital Do Coracao — São Paulo, Brazil (enrolling)
• Hospital Clinico UC Christus — Santiago, Chile (enrolling)
• Fundacion Valle del Lili — Cali, Colombia (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.