Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Hypertension (Without Type 2 Diabetes Mellitus), High Blood Pressure, Male, Female, Adult, Cognition, Endothelial Function (Reactive Hyperemia), Oxidative Stress, Diet, Overweight, Body Composition Measurement, Gut Microbiome, Arterial Stiffness, Caucasian Whites, Inflammation, Microvascular Function

In brief

The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.

Key facts

Study ID: NCT06735599
Run by: Georgia State University
People needed: 40
Starts: 2024-09-17
Expected to finish: 2027-01-01
Last updated by the study team: 2026-03-27

Who can join

Age: 45 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Individuals 45-65 years of age
Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and/or diastolic blood pressure = 80-89 mmHg) for at least 6 months
BMI 25-35 kg/m2 via anthropometric measurements.
Ability to give consent

You may not qualify if…

Allergies to berries
Use of one hypertensive drug for less than three months
Use of more than one anti-hypertensive or statin drug, insulin, antibiotics, and anti-inflammatory drugs, active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological disorders or severe head injury
Smoking
Alcohol consumption (>2 drinks/day)
Consuming antioxidant, probiotic, and prebiotic supplements
Pregnant or lactating
Participating in a weight loss program

Where it is running

Georgia State University — Atlanta, Georgia, United States (enrolling)

Full record on ClinicalTrials.gov

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