Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer

Recruiting now · Not applicable

Conditions studied: Gastric Cancer

In brief

Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging. This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients. A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.

Key facts

Study ID

NCT06735105

Run by

Yunnan Cancer Hospital

People needed

129

Starts

2023-12-23

Expected to finish

2024-12-31

Last updated by the study team

2024-12-16

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The patient was diagnosed with gastric cancer by pathological biopsy
• No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image
• No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases.

You may not qualify if…

• The image quality cannot meet the diagnostic criteria;
• Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.

Where it is running

• Yunnan Cancer Hospital — Kunming, China (enrolling)

Full record on ClinicalTrials.gov

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