Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars with Irreversible Pulpitis
Recruiting now · Not applicable
Conditions studied: Dental Caries, Irreversible Pulpitis
In brief
This study evaluates the effectiveness of photobiomodulation (PBM) in conjunction with mineral trioxide aggregate (MTA) pulpotomy for treating irreversible pulpitis in immature first permanent molars. PBM, also known as low-level laser therapy (LLLT), is used to enhance healing, reduce inflammation, and manage pain in young teeth. The randomized clinical trial involves 72 children aged 6-9 years, divided into two groups: one receiving MTA pulpotomy alone and the other receiving MTA pulpotomy with PBM. Clinical and radiographic outcomes will be assessed at intervals over 15 months. This research aims to determine the combined therapy's efficacy in improving pulp healing and reducing post-operative discomfort compared to MTA alone.
Key facts
- Study ID
- NCT06730360
- Run by
- Mansoura University
- People needed
- 72
- Starts
- 2024-10-10
- Expected to finish
- 2026-04-05
- Last updated by the study team
- 2024-12-17
Who can join
Age: 6 and older, up to 9. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Children aged 6 to 9 years.
- Non-contributory medical history (healthy otherwise).
- Presence of carious first permanent molars with the following characteristics:
- Deep caries extending to ≥2/3 of dentin.
- Positive response to cold testing.
- Clinical diagnosis of irreversible pulpitis (moderate or severe), with or without periapical periodontitis.
- Restorable tooth.
- Probing pocket depth and mobility within normal limits.
- No signs of pulpal necrosis, including sinus tract or swelling.
You may not qualify if…
- Insufficient bleeding after pulp exposure (indicating necrotic or partially necrotic pulp).
- Presence of systemic or medical conditions that may contraindicate participation.
- Teeth with unrestorable structure.
- Teeth showing signs of pulpal necrosis, such as the presence of a sinus tract or swelling.
Where it is running
- Faculty of Dentistry — Al Mansurah, Dakahlia Governorate, Egypt (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.