Pleural Irrigation With a Novel Devise.

Recruiting now · Not applicable

Conditions studied: Pleural Effusion Disorder

In brief

Single-arm pilot trial of the use of intrapleural saline irrigation to treat retained pleural infections for patients with contraindications to standard of care intrapleural enzymatic therapy.

Key facts

Study ID

NCT06727578

Run by

Beth Israel Deaconess Medical Center

People needed

10

Starts

2025-05-25

Expected to finish

2026-07-31

Last updated by the study team

2025-07-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Retained pleural effusion identified via bedside ultrasound within the first 24 hours after chest tube insertion
• Patient is contraindicated from receiving intrapleural enzymatic therapy within the first 24 hours after chest tube insertion

You may not qualify if…

• Non-infectious cause of pleural fluid analysis findings listed above identified (e.g. malignancy)
• Post-procedural empyema or complicated parapneumonic effusion

Where it is running

• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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