Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism

Recruiting now · Not applicable

Conditions studied: Insulin Resistance

In brief

Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels. Subjects will be provided with a standardized diet (55/15/30% CHO/PRO/FAT) prior to collection of pre-intervention data of insulin sensitivity. Individuals will then participate in an 8-week electrical stimulation intervention (30min/day, 3x/week) and randomized into placebo/control, NMES, resistance training combined with NMES (RT +NMES), or resistance training (RT) group (n=20 per group), followed by collection of post-intervention data. The control group will receive electrical stimulation up to sensory level, the NMES group will receive stimulation up to tolerable intensity to induce visible muscle contraction, the RT+ NMES will receive stimulation up to tolerable intensity during resistance training, and the RT group will only receive exercise training. Control and NMES group will self administer stimulation at home. Pre-and post-intervention data includes measurements for body composition, resting metabolic rate, VO2max, insulin sensitivity, and comprehensive blood work.

Key facts

Study ID

NCT06722391

Run by

University of Texas, El Paso

People needed

80

Starts

2024-08-19

Expected to finish

2031-09-01

Last updated by the study team

2024-12-09

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Overweight/Obese (BMI ≥25)
• Sedentary Lifestyle: Physical Activity Level\<1.4
• Less than 150min/week of structured Exercise

You may not qualify if…

• Use of anti-hypertensive, lipid-lowering or insulin sensitizing medications
• Excessive alcohol, drug abuse, smoking
• Pregnant Women
• Unwilling to adhere to the study Intervention

Where it is running

• University of Texas at El Paso — El Paso, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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